Question by dancing67: How does dr do nitration with cpap or what is nitration?
I have been diagnosed with obstructive sleep apnea a month ago, was for sleep studies, got a temporary tracheostomy and septum plasty, now in this week has to go for nitration and cpap machine. what do they mean with nitration?

Best answer:

Answer by gangadharan_nair
Obstructive sleep apnea comprises episodes of partial and/or complete closure of the upper airway during sleep leading to breathing cessation, defined as > 10 sec. Symptoms include restlessness, snoring, recurrent awakening, morning headache, and excessive daytime sleepiness. Diagnosis is based on sleep history, physical examination, and polysomnography. Treatment is with nasal continuous positive airway pressure, oral appliances, and, in refractory cases, surgery. Prognosis is good with treatment, but most cases are undiagnosed and untreated, resulting in hypertension, heart failure, and injury and death from motor vehicle and other accidents resulting from hypersomnolence.
Long-term intermittent hypoxia increases nitration and oxidation in many brain regions including those involved in sleep/wake control. A major source of longterm intermittent hypoxia -induced nitration appears to be inducible nitric oxide synthase (iNOS):
CPAP means Continuous Positive Airway Pressure.
Please see the web pages on CPAP and Google search on Nitration with CPAP.

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